Conan O'Brien was roasted by leading American comics ... as well as wife Liza Powel O'Brien, 54, and son Beckett, 19, as he was honored with the Mark Twain Prize for American Humor on Sunday ...

They wed in January 2002 and went on to have two children, a daughter, Neve, and a son, Beckett. Don't miss: Conan O'Brien's ...

Conan O'Brien has had quite the illustrious career ... When Liza's parents spoke to The Seattle Times about their son-in-law in 2010, they revealed that it was only a year or so after Liza ...

O'Brien was surprised how much free time Javier Bardem had in Madrid for his "Conan O'Brien Must Go" travel series. “He doesn't have enough work.” ...