It also focuses on the macula densa (MD) cells, located at the vascular pole of each nephron. Nephrons are the structural ...

Each kidney contains over one million microscopic filtering units called nephrons. Each nephron is made of a tubule and is responsible for 'cleaning' the blood by removing urea and excess water ...

Genetic studies performed in humans and mutant mice have implicated a number of critical genes, in utero environmental factors and molecular mechanisms that regulate nephron endowment and kidney size.