Ancient viral infections have left endogenous retroviruses in our DNA, impacting genomic evolution and playing roles in health and disease mechanisms.

Biotech firms are engineering smarter, safer gene delivery systems to enhance the safety and efficacy of genetic medicines.

Since their first clinical trial 20 years ago, retroviral (gretroviral and lentiviral) vectors have now been used in more than 350 gene-therapy studies. Retroviral vectors are particularly suited ...

It is therefore necessary to recognize which genes are most frequently hit by retroviral insertion ... role in chromatin structure modeling and thus in gene transcription control.

Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene ...