the action of the complement system is context-dependent and low levels of chronic complement activation has in some situations been reported to be pro-tumorigenic, though the data that underpins ...

In organ specific autoimmune disease, inappropriate activation of the complement system amplifies the pathology of human and/or experimental diseases, including rheumatoid arthritis, multiple ...

reveal an unexpected role for complement proteins ... to immune- and nervous-system function. Future work will unpick the links between synaptic activity and activation of the complement cascade ...

Deficient or excessive activation of the complement system may lead to severe disorders, including micro-thrombotic, autoimmune, and neurological diseases that can have severe or even fatal ...