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Uncovering the role of mitochondrial genome in pathogenicity and drug resistance in pathogenic fungi
T-2307 inhibits the activity of mitochondrial complexes III and IV in the electron transport chain. ML316 suppresses the mitochondrial phosphate carrier Mir1, thus reducing the generation of ATP.
More information: Jonathan Valeros et al, Rhodoquinone carries electrons in the mammalian electron transport chain, Cell (2025). DOI: 10.1016/j.cell.2024.12.007 Journal information: Cell ...
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