T-2307 inhibits the activity of mitochondrial complexes III and IV in the electron transport chain. ML316 suppresses the mitochondrial phosphate carrier Mir1, thus reducing the generation of ATP.

More information: Jonathan Valeros et al, Rhodoquinone carries electrons in the mammalian electron transport chain, Cell (2025). DOI: 10.1016/j.cell.2024.12.007 Journal information: Cell ...

The IFO Institute’s Dr Klaus Wohlrabe presented new survey findings, showing increased supply chain diversification, expanded inventories, stronger regional sourcing and greater production flexibility ...

The cells’ mitochondria skip a key metabolic reaction that takes place in other cells in the body, a study finds. Created by editing the gray wolf genome, two dire wolves are the subject of ...

A decrease in TCA cycle activity may lead to impaired nutrition metabolism and cellular energy shortage. Herein, we aimed to characterize the detailed metabolic changes that compensate for energy ...

Each chromatophore in turn contains hundreds of cooperating proteins that together absorb the energy of sunlight and convert and store it in molecules of ATP, the universal energy currency of all ...