The San Francisco 49ers have some work to do to get their offense back on track after a rough 2024 season. While getting ...

San Francisco 49ers running back Isaac Guerendo is set to return from foot and hamstring injuries and play Monday vs. the Lions.

Curious to know about 49ers RB Isaac Guerendo‘s injury? The standout rookie has drawn attention for his breakout performances on the field and his determination to play despite a recent foot injury.

With their top two options sidelined, the expectation was that rookie Isaac Guerendo would lead the backfield for the remainder of the regular season. Well, Guerendo suffered an injury of his own ...

San Francisco 49ers running back Isaac Guerendo gave a positive update on his knee injury Monday, noting he did not tear his ACL as some had speculated: ACL is good, thank you GOD. I'll be back ...

The Broncos signed three players who participated in last year’s East-West Shrine Bowl, including LB Levelle Bailey and RB ...

Unfortunately, the season finale came with one final trick up its sleeve as running back Isaac Guerendo was carted off the field early in the first quarter. On the broadcast, sideline reporter ...

Guerendo has been diagnosed with MCL and ankle sprains in his left leg following an MRI on Monday, Matt Barrows of The Athletic reports. The 49ers' 2024 campaign is over, but the team's season ...

San Francisco 49ers rookie Isaac Guerendo didn't transition to playing running back until he arrived at Wisconsin. Before that, he was a wide receiver but understood a position change was ...

Isaac Guerendo is expected to step in as the San Francisco 49ers' starting running back after injuries to Christian McCaffrey and Jordan Mason. Guerendo, a versatile fourth-round rookie from ...

While the Lions are preparing to make a deep run in the playoffs, the 49ers have lost their last two games and have dropped five of their last six matchups. The 49ers last met Detroit in the NFC ...

San Francisco 49ers rookie running back Isaac Guerendo's 15-yard rushing score gives the 49ers their first touchdown of their "Sunday Night Football" road game against the Buffalo Bills in Week 13 ...