Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

The San Diego Padres (88-66) take on the Chicago White Sox (36-118), who will be trying to halt a three-game losing streak, ...

New York Post reporter Jon Heyman linked the Padres with Mets first baseman Pete Alonso. The four-time All-Star and 2019 NL ...

Fernando Tatís Jr., Manny Machado and Donovan Solano gifted the San Diego Padres with plenty of insurance against the Houston ...

The San Diego Padres beat the Houston Astros on Thursday behind another dominant performance on the mound from Dylan Cease, ...

There’s a lot of baseball still to be played before the World Series comes our way in late October, but the three-game series ...

Astros starter Framber Valdez made one mistake in seven innings, and it ended up handing him a tough-luck loss as he was ...

Analyzing Wednesday’s Houston Astros at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

Jurickson Profar and the San Diego Padres face Matt Chapman and the San Francisco Giants at Oracle Park on Saturday. First ...

The Minnesota Twins’ decision to stand pat at the trade deadline, despite glaring bullpen needs, has backfired. Meanwhile, ...

The Chicago White Sox trailed by two runs as Sosa batted with a runner on and two outs in the ninth inning against the San Diego Padres at Petco Park. After a ball, Sosa fouled off the next three ...

BOTTOM LINE: The Chicago White Sox, on a three-game losing streak, take on the San Diego Padres. San Diego is 43-36 in home games and 88-66 overall. The Padres have a 37-20 record in games when they ...